Barely Significant
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might be significant

2,429 sentences · 2,429 papers · 8,858 search hits before verification · confirmed specimen

Sighted at

p=0.065p=0.54

Listed by Hankins, posted since

In the literature

Different research projects suggest that the role of T lymphocytes might be significant in tumour development. iNKT cells are a new subpopulation of T cells and show cytotoxic activity against tumours. iNKT cells participate in modulating the function of other cells which have anti-tumour properties and secrete cytokines, which have pro-inflammatory and anti-inflammatory effects.
These controversial findings suggest that the interplay of several cytokines involved in angiogenesis and microvascular permeability, besides VEGF, might be significant in the pathogenesis of POEMS syndrome, at least by explaining some of its clinical features such as extra-vascular volume overload (ascites, pleural effusion and oedema), skin angioma, papilloedema and presumably peripheral neuropathy [ 7 , 15 , 17 , 20 ].
Moreover, the low level of conservation in the EREs of estrogen-responsive genes between mouse and human suggest two consequences: first, that the core physiologic estrogen effects such as sex differentiation/mammary gland development may be mediated by a small set of highly conserved and similarly regulated ER-responsive genes; and second, that there might be significant differences between downstream estrogen effects between mouse and human.
23 They might be significant as a source of creativity. 24 They may be experienced as socially and personally significant, conferring a particular sense of self-identity as a voice hearer and providing a source of meaning. 25 Spiritually significant voices may or may not be significant for any or all of these reasons, but they are distinctive by virtue of the spiritual interpretation that is placed on them or—perhaps more correctly—is an integral part of the experienced voice.