“moderately significant”

In the cellular component category, the Extracellular Space had a moderately significant association with a count of three genes.

Averting the persistence of TNF-α -associated inflammation and restoring immune regulation has been the main target of biological therapies, whereby TNF-α blockade using monoclonal antibodies has been widely used to treat autoimmune diseases such as rheumatoid arthritis [ 18 , 19 ] and ulcerative colitis [ 20 ], and this could potentially be useful in reducing inflammation in podoconiosis, though a lot more research is required before reaching this step as the increase in TNF-α - in the patients is only moderately significant.

This effect is statistically moderately significant and occurs primarily in the case of men.

46 Where there is biological similarity in the relationships assessed by individual tests, a biological pattern of moderately significant results is very unlikely to occur by chance.