Barely Significant
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nearly significant

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p=0.0579p=0.06

Listed by Hankins, posted since · Hankins (2013) · Otte et al. (2022)

In the literature

The effects of the addition of significant interaction terms are illustrated (see Appendix B for our approach to graphical modeling) for the ratio of apoA-I/HDL-P ( Figure 2 ), and medium HDL-P ( Figure 3 ), and for the nearly significant HDL-C interaction ( Figure S1 ), and for the marginally significant HDL particle size interaction ( Figure S2 ).
In a multinational clinical trial using indapamide (and perindopril as needed) in participants over 80 and with a sustained blood pressure greater than 160 mm Hg, there was a reduced risk of CHF and death, as well as a nearly significant effect on stroke. 30 In analysis of the REasons for Geographic And Racial Differences in Stroke (REGARDS) study, investigators found that disparities in stroke incidence resulting from HTN between non‐Hispanic blacks and whites were significantly blunted in those ≥75. 31 Whether HTN needs to be as aggressively treated in the elderly, as suggested by recent reports of greater decline in total brain volume 32 and increased risk of falls in this population, 33 remains to be answered.