Other studies in Mexican-Americans and Taiwanese Chinese in sample sizes of NPDR/PDR varying from 103 to 437 revealed the association of borderline significance with a few SNPs.[ 37 54 55 56 ] However, all these associations need to be replicated to draw any meaningful biological conclusion.
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“of borderline significance”
In the literature
In Tanzania, another trial of insecticide spraying after mass distribution of antibiotics led to a 39 % lower prevalence of trachoma after six months spraying; although this was of borderline significance, after 12 months there was no difference in trachoma prevalence despite consistent reductions in M. sorbens abundance [ 11 ].
While there were some results of borderline significance, they were neither strong nor consistent across the different analyses.
Knee pain was of borderline significance in cross-sectional analyses but became significant over time.
If, instead of fitting the dependence of myelination on local axon density, we simply counted the fraction of oligodendrocytes that myelinated, by averaging over all the sampled images, then the results were broadly similar, except that NMDA receptor block in control conditions produced a reduction of myelination of borderline significance ( Figure S3D ).
The principal components did not vary by insecticide treated bednet (ITN) use, and RTS,S/AS01 E vaccination was associated with reduction in the first principal component of borderline significance ( Table S2 ).
These associations remained significant after further adjustment for BMLs, except that the longitudinal association at the patellar site decreased in magnitude and became of borderline significance (Table 2 ).
Although in univariate analysis we observed a lower mean fractional tubular phosphate reabsorption among patients on TDF-ART than those on Non-TDF ART, the differences were of borderline significance and disappeared in multivariable analysis.
Although we observed no difference in risk estimates for the association between solvent exposure and ALL risk, our analyses have shown that association between paint exposure and ALL risk was statistically significant for cases with chromosomal structural changes in leukemic cells (OR = 1.96; 95% CI, 1.24–3.10) but of borderline significance for those with numerical changes (OR = 1.48; 95% CI, 0.99–2.21).
The association of total cathepsin S with ENI was of borderline significance in a multivariable analysis corrected for multiple comparisons with an OR per SD increase in log-transformed total cathepsin S of 0.54 (95%CI, 0.35 to 0.81). 3.2.5.
At the environmental/structural level, the odds of testing HIV-positive increased by 12% for every five arrests for having track marks, although this association was of borderline significance.
CRP levels were of borderline significance.
Stage 1 showed a slightly increased HR (1.13) of borderline significance and the HR increased further in stage 2 (1.41).
A decline of borderline significance at 20.1% was documented for NMR in boys, and the NMR for boys and girls was similar in 2016 (Table 1 ).
The same applied to p-p70S6K, but this correlation was of borderline significance.
There were also a higher percent of the women without any comorbidity at all, although this was only of borderline significance.
AIF DCE gives a v e treatment p value of borderline significance, whilst AIF POP and AIF PB are not significant, indicating AIF DCE may be the best approach if only v e is of interest.
However, the difference between the sites was revealed to be merely of borderline significance (p-value 0.052, overlapping confidence intervals).
However, it was noted that the graphically apparent protective effect of APOE‐ ε 2 was of borderline significance and the number of subjects carrying 2/4 ( n = 25) and 4/4 ( n = 30) combinations was small relative the number carrying 3/4 ( n = 225).
When under-five child mortality was added to the previous multivariate model, the relationship between non-receipt of a vitamin A capsule and previous under-five child mortality in the family was of borderline significance (PR 1.03, 95% CI 0.99–1.08).
Increased tumor size ( p = 0.01), presence of metastasis ( p < 0.001), presence of epithelioid cell morphology ( p = 0.008), involvement of iris ( p = 0.02), ciliary body involvement ( p = 0.02), absence of intrascleral location ( p = 0.02) and presence of extrascleral location ( p = 0.09) adversely affected OS, the latter association of borderline significance.
To satisfy the proportional hazard assumption, we relaxed the criterion in the last step by allowing non-demographic variables of borderline significance (i.e. p value between 0.05 and 0.10) to be individually added into the Cox-PH regression model.
The corresponding 1-year risk for MI was of borderline significance at 1.38 (95% CI: 1.00-1.77) .
Lactate, which has a well-known predictive value in sepsis, showed a positive association of borderline significance with omentin-1.
18 There was a substantial reduction of borderline significance in the proportion of potentially toxic concentrations (>20 mg/mL), which have been associated with kidney toxicity. 19 – 21 This finding warrants further investigation to confirm this observation.