When looking deeper into individual opioid types ( figure 3 , table 4 ) there was a significant rise in natural and semi-synthetic (prescription) opioid death rates (rates per 100 000 overall: 1.4 to 5.1, p<0.001; rates per 100 000 women: 1.1 to 4.8, p<0.001; rates per 100 000 men: 1.6 to 5.4, p<0.001) and heroin (rates per 100 000 overall: 1.2 to 6.3, p<0.001; rates per 100 000 women: 1.1 to 4.9, p=0.056 (on the boundary of significance); rates per 100 000 men 1.3 to 7.7, p<0.001).
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Self-esteem had a significant effect on proportion of negative attributes, F (3, 51) = 0.7.1, p < .05, η p 2 = .13, and was on the boundary of significance with differential importance, F (3, 44) = 4.07, p = .05, η p 2 = .09.
Similarly, the serum olanzapine concentration at week 4 could predict the change in body weight ( β = 0.376, p = 0.013) with the model adjusted on the boundary of significance ( p = 0.056).
An improved OS on the boundary of significance was also observed (83.8 vs. 72.8%, HR, 0.54, 95% CI, 0.29–1.03, P = 0.058).
low CXCR5 + CD8 + T cells group was on the boundary of significance in TCGA cohort ( n = 184, P = .0582; figure 2(f )).
This same relationship for males is only on the boundary of significance, with males who use both having 39% higher odds of a respiratory condition compared to males who use neither (AOR 1.39 [95% CI 0.99–1.97], P = 0.06001).
Women had longer PFS and OS than men in the AVALANCHE, however, only OS was on the boundary of significance (P=0.071).
No significant differences were found in the characteristics of participants between 2016 and 2017 according to the Fisher Exact test (p>0.05 for all variables) as shown in Table 2 . Burnout substantially decreased (48% to 25%) over the year of this project showing a medium effect size (Cohen’s h = 0.490) while being on the boundary of significance (p = 0.097).
was statistically significant only for lariciresinol ( p < 0.05) and on the boundary of significance only for total lignans ( p < 0.1), showing lowering the odds of abnormal values about 42 and 38%, respectively, with each increment of tertile category.
All P -values less than 0.05 were deemed significant, whereas those between 0.04 and 0.05 were considered marginally significant, and those between 0.05 and 0.10 were assumed to be on the boundary of significance.
A higher hypo-responsivity intercept was associated with higher autistic traits ( b = 0.06, 95% CI [0.01, 0.11], p = 0.011, B = 0.49) and ADHD traits at age 3 ( b = 0.25, 95% CI [0.00, 0.49], p = 0.051, B = 0.39), although the latter on the boundary of significance.
Given that our result is only on the boundary of significance, we are reluctant to make claims about the modulating role of state-trait emotion interactions in subjective probability at this point.
However, this interaction was only on the boundary of significance and had very modest evidence for inclusion (BF Inclusion = 1.35).
Again, similar to sex, physicians reported significantly higher percentages of agreement to the items of “workload control”, “manageable work-related stress”, and “lack of burnout” (burnout p-value on the boundary of significance: 0.06).
Linear effect of PSS was on the boundary of significance but showed the same trend.
Since FI is based solely on the boundary of significance, the linear association of FI with event counts will remain regardless of statistical methodology or outcome measure.
Raw data ( W =0.9648, P <0.006) were non-normally distributed, and log-transformed data ( W =0.979, P <0.08) were on the boundary of significance.
Naloxone prescriptions demonstrated an estimate on the boundary of significance in the shorter follow-up period (aHR [95% CI]: 1.29 [0.96, 1.74]).
Additionally, three treatment strategies did result in a protective association with relapse being on the boundary of significance but all-drug overdose being insignificant.
AI/AN/NH students who used alcohol also showed increased odds of suicidal ideation, but this association was on the boundary of significance (Table 2B ).
The Bai ethnic group with P = 0.057 is on the boundary of significance and needs further investigation regarding the effects of lifestyles.