Barely Significant
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“showed a trend”

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In the literature

Additionally, although statistically not significant, the between-group comparison in the 1st PET scan with and without food intake in our human experiments showed a trend toward slightly higher V T values in the food-intake group, while the within-subject comparison in the 1st PET scan in our rat experiment (Experiment 1) showed a trend toward slightly higher BP ND values for the scan of the non-feeding condition day.
20 Regarding disease progression, a study (C-OPERA) comparing a group of patients under CTZ+MTX combo versus a group of placebo + MTX patients showed a trend of greater modified Total Sharp Score change from baseline independently of positive titres of anti-CCP in both groups. 21 In another study comparing the efficacy of CTZ versus adalimumab, there were no baseline differences in anti-CCP positivity nor in the efficacy endpoints regarding the anti-CCP result. 22 This study has significant limitations inherent to its design, which implies a selection bias.