Older participants showed a trend of performing better than younger participants (YA: mean ± SD = 80.8 ± 7.9%, OA: 85.1% ± 6.5%), but this difference did not reach statistical significance ( z = –1.8, p = 0.07, Mann–Whitney U -test).
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Compared to vehicle treatment, Kae, Que, VitC, and Dla treatment significantly decreased total ROS accumulation in DMD hiPSC-CMs while Dios, Nar, Oxl only showed a trend ( Figures 5A,B ).
Despite no significant difference was detected in all clinical evaluations, it could be highlighted that patients telemonitored at home showed a trend toward a better clinical picture ( Table 3 ).
[ 38 ] Angiotensin-converting enzyme inhibitors (ACEIs)/Angiotensin receptor blockers (ARBs)Concerning ACEIs, perindopril was the first drug that showed a trend to reduce the primary endpoint of HF hospitalization or all-cause death in the PEP-CHF (Perindopril for Elderly People With Chronic Heart Failure) trial (HR = 0.69, 95% CI: 0.47−1.01; P = 0.055).
The results showed a trend toward upregulation, but without statistical significance.
In general, inflammatory markers showed a trend towards higher levels in patients with MAFLD, however, only CPK showed statistical significance.
The interstitial scores showed a trend to decrease by ISD017 treatment, although it did not reach statistical significance (Supplementary Fig. 5).
Mode of treatment of chronic GvHD that is, systemic therapy alone [Systemic therapy alone versus (Systemic Therapy + Local Therapy and Local Therapy alone)] ( p = 0.052) showed a trend for development of TB.
However, other beiging‐related genes, such as Cd137 ( Tnfrsf9 ) and Tmem26, only showed a trend towards an increase in young adult LP‐fed mice compared with HP‐fed mice (Fig. 6C ).
pylori -infection and in short-term view showed a trend for reversal after eradication.
3 c,d), whereas MMP13 expression was not significantly modulated, and showed a trend towards reduced expression in all TNAP-transduced groups (Supplementary Fig. 3 d).
However, levels of GM-CSF, IFNγ, TNFα, IL-17A, CCL2, and CXCL10 showed a trend of decrease in the K group compared to the W group.
Those with a skin type less likely to burn (Fitzpatrick scale type 4 or 5) showed a trend towards fewer sun safety practices compared to those with type 1 or 2 skin, however this did not reach statistical significance.
Interestingly, fish exposed to the higher concentration showed a trend towards a decreased locomotor activity.
A comparison before and after the study showed a trend toward a reduction in the incidence rate of nosocomial infectious diseases, a reduction in the overall cost of antibiotics and a reduction in the selection for multidrug resistant bacteria, thus improving patient safety.
However, the LP, MP, and HP groups showed a trend of separation, and the metabolites among the three groups were different.
Interestingly, rabbits spent significantly more time hiding in the 6-pen trial compared to the 3-pen trial, and showed a trend towards higher rearing, chewing, and self-grooming activities in the 3-pen trial compared to the 6-pen trial, though no statistically significant differences were reached in those three behaviors ( Table 2 ).
Indeed, in a first pilot study in COVID-19 patients requiring intensive care, high-dose IV vitamin C significantly improved oxygenation, reduced organ-damaging cytokine storm (IL-6), and showed a trend towards reduced mortality in severely ill patients [ 49 ].
We also found PMRs of these 10 markers showed a trend of stepwise increase with the progression of CRC (Additional file 1 : Figure S2), indicating these markers maybe useful for cancer staging.
ICAM-1 showed a trend towards increased levels in CTEPH-ECs but did not reach significance ( p = 0.07).
The vitamin D uptakes in lysoPC mixed micelles showed a trend similar to that in NoPC mixed micelles; that is, vitamin-D 5 uptake tended to be lower than that of other vitamins D, but not statistically significantly different from that of vitamins D 3 , D 6 , and D 7 .
Patients with fractures showed a trend of lower stiffness and failure load at both bone sites (Table 3 ).
Finally, WIP1 protein showed a trend towards increased expression after Nut-3a treatment in the TP53 -wt cells, ( Figure 4 C and Figure S3 ), while being downmodulated by the drugs and their combination in NOMO1 cells ( Figure 4 D and Figure S3 ). 3.5.
In a cohort of 498 BC patients followed for five years, they observed that the TaqI minor allele showed a trend toward an increased risk for breast cancer-specific mortality.
In the SARC, KIRC, and BLCA cancer types, lipid activity showed a trend opposite to the survival rate in the high EMT group.