“showed a trend”

Two other similar studies [ 23 , 28 ] also showed a trend toward increased mortality with the use of non-WBC-reduced blood.

However, when the investigators looked for evidence of changes in organ function and adequate tissue oxygenation, the results were strikingly different: urine output decreased, capillary blood flow showed a trend to decreasing values, and capillary red blood cell velocity did not change.

Although mortality did not differ between groups, the RCT showed a trend toward reduced duration of mechanical ventilation and length of stay in the intensive care unit in patients receiving furosemide + albumin.

Similarly, in addition to the impact of increasing KIR3DL1 effective counts on KIR3DS1 transcript expression, individuals with the protective genotype of an effective copy of KIR3DS1 and two effective copies of KIR3DL1 showed a trend towards an expansion of KIR3DS1+ NK cells in the peripheral circulation, as compared to individuals with a single effective copy of KIR3DL1 in the presence of an effective copy of KIR3DS1 ( Figure 5D,E ).

In four unblinded randomized studies, compared with placebo, somatostatin showed a trend toward benefit, with an overall risk reduction by 17% [ 6 ].

Transferrin levels only showed a trend to inverse correlation with the sole M20 ECD strength, even though they did not approach significance ( Table 3 ). 4.

Although this study showed a trend toward superiority of denosumab versus zoledronic acid in delaying the time to first on-study SRE in patients with advanced solid tumors and multiple myeloma, further trials in myeloma patients are needed to support the use of denosumab in this population.

an interim analysis from the SAILOR study showed a trend for an increase in the incidence of stroke in the group treated with 0.5 mg of ranibizumab [ 47 , 48 ].

While not significant (p = 0.055), the contrast between low treatments in Expt 2 and 3 showed a trend of lower survivorship in Expt 3 as compared to Expt 2.

Although these N4 B6- Prop1 -/- mice showed a trend towards increased serum ACTH compared to wild type and heterozygote littermates, the difference was not significant.

The results of this study showed a trend toward the reduction in the incidence of metastasis, although not statistically significant, in groups in which zoledronic acid was preventively administered.

An investigation of human post-mortem brain tissue recently showed a trend for reduced DRD4 mRNA expression in samples carrying at least one seven-repeat allele [37] .

29 , 30 One study with a small cyclist sample size showed a trend toward lower spine BMD in cyclists compared with controls. 33 Heinonen et al 10 found no significant difference in weight-adjusted BMD at the femoral neck and lumbar spine in cyclists compared with active controls.

We also found that genes inhibited in the miRNA transfection experiment, irrespective of TargetScan annotation, showed a trend of negative associations with miRNA expression in our time series dataset ( Figure 5B–C ).

TX showed a trend toward increased pCR in patients with poor prognostic factors and hormone receptor-positive tumors [ 6 ].

The patient-reported pain scores showed a trend favoring OBM, but the difference was not significant (P=0.11).

The decrease continued for at least 10 hours and then some of them, such as mlncR21, showed a trend of recovering to the level in untreated tissues.

Finally, the younger children were slower to detect a gaze change, while the older children and the adults only showed a trend toward the same effect.

Interestingly, sleep-deprivation-induced changes in acute blood pressure and cognition across the night showed a trend for positive correlations, especially at the 1:00 AM testing.

Treatment for 24 hours with CsA showed a trend towards an increase in CTGF gene expression, which was not statistically significant.

The bladders were weighed and showed a trend of lower bladder weight after treatment with both agents ( Figure 5C ).

The ultimate tensile stress was not significantly different between groups though the PGE 2 groups showed a trend to be stronger than the sodium chloride injected group (Table 1 ).

Although the differences were not statistically significant due probably to the small number of the patients tested, the minor genotypes showed a trend toward being associated with non-SVR, and with non-RVR to a lesser extent, in HCV-2a and -2b infections, as has been reported for HCV-1a and -1b infections [21] – [23] .

Although it was not statistically significant, the efficacy data in the other outcomes also showed a trend favoring oral solubilized UDCA.

Pretreatment with both AAV8.DN.ERK and AAV8.DN.p38 showed a trend towards even better survival (66 % mortality by 7 days) than AAV8.DN.ERK alone.