Effect of antiretroviral therapy on decreasing arterial stiffness, metabolic profile, vascular and systemic inflammatory cytokines in treatment-naïve HIV: A one-year prospective study.

PLoS One · 2023 · PMC10022802 · PMID 36930649

Europe PMC DOI

hedged sentences

0.0630

closest p · 1.3× alpha

0.0630

boldest claim

The sentences

showed a trendp = 0.063so close (0.05 < p ≤ 0.1)

After ART, most biomarkers of inflammation significantly decreased (p<0.01), except for D-dimer which showed a trend toward a significant decrease (p = 0.063).

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an overall trendno p-value reported

In our study, we observed an overall trend toward a significant decrease in D-dimer post-ART.

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a strong trendno p-value reported

did not reach statistical significanceno p-value reported

I would say something like ‘The hs-CRP showed a strong trend towards decrease, however, this did not reach statistical significance. hs-CRP, despite ART, remained significantly higher in ART-experienced persons when compared to the control group.’ line 265-270: This is all true.

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a trend toward significanceno p-value reported

Rather state a trend toward significance for accuracy. line 205: Again, consistent use of wording to refer to the study groups.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.