Genetic insights into ossification of the posterior longitudinal ligament of the spine.

As for the skeletal muscle cell group, we did not discuss it here because it was suggestive but not significant (P=0.059). p11, L254 “We conducted partitioning heritability enrichment analyses to investigate cell groups related to OPLL.

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The result of genetic correlation analysis for osteoporosis barely did not reach the false discovery rate (FDR)-corrected significance level, but we included it in the MR evaluation because there have been several previous reports of a strong trend toward whole-body ossification in OPLL patients ( Hukuda et al., 1983 ; Mori et al., 2016 ; Nishimura et al., 2018 ; Yoshii et al., 2019 ).

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Line 316ff PRS scores – these β values may be significant but they are small.

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Especially, the expressions of WWP2 , EIF3H , and SNX17 showed nominally significant differences (see ‘Materials and methods’ and Figure 1—figure supplement 10 ).

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