suggestive but not significantp = 0.018
This locus contains several interesting genes, with four genes ( Ankrd11, Spg7, Rpl13 and Fanca ) each possessing nonsynonymous mutations in one of the HMDP Recombinant Inbred founders and another, Abcb10 , showing correlation with ISO-treated heart weights ( R = 0.33, p = 1.3 × 10 −3 ) and a suggestive but not significant cis-eQTL( p = 0.018).