Paradoxical Effects of Prolonged Insufficient Sleep on Lipid Profile: A Pooled Analysis of 2 Randomized Trials.

J Am Heart Assoc · 2023 · PMC10757551 · PMID 37815115

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.2900

boldest claim

The sentences

failed to reach statistical significanceP =0.051so close (0.05 < p ≤ 0.1)

Inverse associations of IL‐6 with LDL‐C failed to reach statistical significance but were stronger in SR than AS (SR: β=−5.3±2.6 mg/dL; P =0.051 versus AS: β=−1.8±5.3 mg/dL; P =0.73).

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did not reach statistical significanceP =0.29not close (p > 0.1)

In analyses stratified by sex+menopausal status, effects of SR on IL‐6 did not reach statistical significance (premenopausal women: β=0.2±0.2 pg/mL; P =0.29; postmenopausal women+men: β=−0.2±0.1 pg/mL; P =0.20).

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approached significanceno p-value reported

However, an interaction of sex+menopausal status with condition approached significance for IL‐6 ( P ‐interaction=0.069), which increased in SR relative to AS in premenopausal women compared with postmenopausal women+men.

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