Proteomic profiling identifies muscle-invasive bladder cancers with distinct biology and responses to platinum-based chemotherapy.

Nat Commun · 2025 · PMC11785721 · PMID 39890781

Europe PMC DOI

hedged sentences

0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

approached significancep = 0.061so close (0.05 < p ≤ 0.1)

The high PSPI1 H-score approached significance ( p = 0.061) in the matched TMA-internal but not in the TMA-validation TMA ( p = 0.36).

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did not reach statistical significanceno p-value reported

8a ), but did not reach statistical significance.

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showed a trendno p-value reported

Although limited by small sample size, PN-CC1 showed poor RFS and OS, while PN-CC4 showed a trend toward longer RFS (Fig. 3b, c ).

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