Current Treatment Strategies for Multiple Myeloma at First Relapse.

J Clin Med · 2025 · PMC11900467 · PMID 40095642

Europe PMC DOI

hedged sentences

0.5710

closest p · 11.4× alpha

0.5710

boldest claim

The sentences

did not reach statistical significancep = 0.571not close (p > 0.1)

Although a trend towards improved median OS was observed in the PVd group it did not reach statistical significance (35.6 months in the PVd group vs. 31.6 months in the Vd group; p = 0.571).

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failed to reach statistical significanceno p-value reported

OS failed to reach statistical significance in patients refractory to proteasome inhibitors, with a median OS of 43.2 months vs. 30 months for the DKd and Kd subgroups, respectively (HR, 0.698; 95% CI, 0.448–1.087).

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showed a trendno p-value reported

While ASCT showed a trend towards better PFS and OS, it did not reach statistical significance.

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