The effects of endoscopic vacuum therapy for non-operative treatment of anastomotic leakage on oncological outcomes in rectal cancer patients.

Langenbecks Arch Surg · 2025 · PMC11950071 · PMID 40146433

Europe PMC DOI

hedged sentences

0.0730

closest p · 1.5× alpha

0.0730

boldest claim

The sentences

a strong trendp = 0.073so close (0.05 < p ≤ 0.1)

NOLT of AL showed a strong trend towards higher success rates than surgical management of AL (76.9 vs. 52.4%; p = 0.073) with no significant differences between early or late AL treatment.

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did not reach statistical significancep = 0.103not close (p > 0.1)

showed a trendno p-value reported

DFS in our cohort showed a trend towards better outcome in patients with AL, which did not reach statistical significance (no AL: 88.0 months, 95%CI [80.3; 95.7]; AL: 102.5 months, 95%CI [88.1; 116.9]; p = 0.103).

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