A specific role for endothelial EPLIN-isoform-regulated actin dynamics in neutrophil transmigration.

Sci Rep · 2025 · PMC12053001 · PMID 40325158

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did not reach statistical significanceno p-value reported

showed a trendno p-value reported

Furthermore, while HUVEC overexpressing EPLIN-α showed a trend towards increased transmigration compared to knockout (KO) cells, this difference did not reach statistical significance (Fig. 6 C).

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a clear trendno p-value reported

While useful, EA.hy cells are less stable than HUVEC cultures due to their tumour-like characteristics, resulting in statistically non-significant TEM data between KO and EPLIN-α re-expressing cells, despite a clear trend.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.