Barely Significant
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Assessment of Serum Cytokine Levels in Keratoconus Patients.

J Clin Med · 2025 · PMC12072575 · PMID 40364209

4
hedged sentences
0.0270
closest p · 0.5× alpha
0.5930
boldest claim

The sentences

near significancep = 0.027actually significant
Similarly, IL-1β levels correlated positively with keratometry indices, with values between r = 0.307 (K1, near significance) and r = 0.345 (Kmax, p = 0.027).

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did not reach statistical significancep = 0.143not close (p > 0.1)
Body mass index (BMI) showed a trend toward higher values in stable KC patients (28.20 ± 7.84 kg/m 2 ) compared to both progressive patients (24.75 ± 3.62 kg/m 2 ) and healthy controls (25.69 ± 4.46 kg/m 2 ), though this difference did not reach statistical significance ( p = 0.143).

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failed to reach statistical significancep = 0.593not close (p > 0.1)
When stratifying the KC patients by disease severity, we observed a counterintuitive trend in IL-6 levels, with concentrations progressively decreasing with increasing disease severity (9.0240 ± 7.6352 ng/mL in mild, 7.0017 ± 5.8027 ng/mL in moderate, and 6.342 ± 3.3310 ng/mL in severe KC), although this pattern failed to reach statistical significance ( p = 0.593).

also in 1,120 other papers

showed a trendno p-value reported
Body mass index (BMI) showed a trend toward higher values in stable KC patients (28.20 ± 7.84 kg/m 2 ) compared to both progressive patients (24.75 ± 3.62 kg/m 2 ) and healthy controls (25.69 ± 4.46 kg/m 2 ), though this difference did not reach statistical significance ( p = 0.143).

also in 13,339 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.