a significant trendP = 0.03
A significant trend was seen between overall mean NPi and the presence of orthostatic hypotension (OR 1.2; 95 % CI 1.0, 1.4; P = 0.03 ).
A significant trend was seen between overall mean NPi and the presence of orthostatic hypotension (OR 1.2; 95 % CI 1.0, 1.4; P = 0.03 ).
A trend for higher NPi was seen with increasing lying systolic blood pressure (regression coefficient 1.60; 95 % CI −0.05, 3.2; P = 0.057 ) and diastolic blood pressure (regression coefficient 0.71; 95 % CI −0.06, 1.5; P = 0.07 ), but did not reach statistical significance.
Further breaking this down into specific NPi severity categories, a non-significant trend for increasing odds of OH was seen at the 40 % threshold, but at the 50 % threshold the odds ratio increased to 4.9 and became highly significant.
Our study also showed a trend towards increasing NPi with rising lying blood pressure, although was likely under-powered to demonstrate this effect.