Personality, Perinatal Anxiety, and Substance Use as Converging Determinants of Post-Partum Depression in South-East Europe.

Medicina (Kaunas) · 2025 · PMC12298266 · PMID 40731779

Europe PMC DOI

hedged sentences

0.0810

closest p · 1.6× alpha

0.0810

boldest claim

The sentences

showed a trendp = 0.081so close (0.05 < p ≤ 0.1)

A final model (pseudo-R 2 = 0.30) identified post-partum state anxiety (OR 1.10 per point, 95% CI 1.05–1.15, p < 0.001) as the independent predictor; neuroticism showed a trend (OR 1.08, p = 0.081).

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approached significancep = 0.081so close (0.05 < p ≤ 0.1)

Neuroticism approached significance (OR 1.08, p = 0.081), implying partial mediation through acute anxiety, whereas extraversion exerted no independent effect (OR 1.00, p = 0.990).

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did not reach statistical significanceno p-value reported

In our sample, preterm delivery occurred in 18% yet did not reach statistical significance for depression after covariate adjustment, suggesting that psychosocial resilience and lower baseline stress may offset biomedical risks.

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