Blood Cultures Time-to-Positivity as an Antibiotic Stewardship Tool in Immunocompromised Children with Gram-Negative Bacteraemia.

Antibiotics (Basel) · 2025 · PMC12383192 · PMID 40868041

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closest p

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a clear trendno p-value reported

Longitudinal surveillance shows increasing prevalence of extended-spectrum β-lactamase (ESBL) and carbapenemase-producing Enterobacterales , with notable geographic variation but a clear trend toward higher rates over time [ 7 ].

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did not reach statistical significancep = 0.062so close (0.05 < p ≤ 0.1)

showed a trendno p-value reported

Shorter TTP showed a trend toward association with worse outcomes (30-day mortality and/or PICU admission), although this did not reach statistical significance (OR 0.860, 95% CI 0.734–1.008; p = 0.062). 2.5.

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