Barely Significant
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Association of Circadian Rhythm Biomarkers and Ambulatory Blood Pressure Monitoring With Prognosis and Outcome in People With Acute Ischemic Stroke: A Case-Control Study.

Cureus · 2025 · PMC12400472 · PMID 40901216

4
hedged sentences
0.0001
closest p · 0.0× alpha
0.0001
boldest claim

The sentences

highly significantp < 0.0001actually significant
In contrast, the mean urinary melatonin level was significantly lower in stroke cases (7.18 ± 1.91 ng/mL) than in controls (14.26 ± 1.98 ng/mL), and this difference was very highly significant (t = 19.93, p < 0.0001).

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a clear trendno p-value reported
A clear trend is observed in salivary cortisol levels, which increase with stroke severity (according to the NIHSS score)-from 113.70 ± 95.15 ng/mL in minor strokes to 176.19 ± 59.17 ng/mL in severe strokes.

also in 19,460 other papers

Although our results did not reach statistical significance, likely due to sample size limitations, the observed trends reinforce the hypothesis that disrupted circadian BP patterns are linked with less favorable neurological and functional recovery [ 18 ].

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.