Aminophylline in acute exacerbation of COPD: Utility and treatment effects in hypercapnic respiratory failure (ACUTE): A pilot observational study.

Lung India · 2025 · PMC12453528 · PMID 40892811

Europe PMC DOI

hedged sentences

0.2340

closest p · 4.7× alpha

0.5170

boldest claim

The sentences

did not reach statistical significanceP = 0.234not close (p > 0.1)

While the reduction in hospital stay did not reach statistical significance ( P = 0.234), a 1.4-day trend was noted, supporting a possible clinical benefit.

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failed to reach statistical significanceP = 0.517not close (p > 0.1)

However, this also failed to reach statistical significance (P = 0.517, t = -0.65) 9 [ Table 2 ].

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showed a trendno p-value reported

A larger trial might confirm this effect [ Table 2 ] Secondary outcomes: ICU stay: Similar to the length of hospital stay, the length of ICU stay also showed a trend towards reduction in the group where the drug was administered (M = 8.73, SD = 3.78) when compared with the historical cohort (M = 9.35, SD = 2.30).

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