Microbiota-immune dysregulation in cervical cancer patients from Western Mexico: linking gut dysbiosis and NK cell exhaustion as promising biomarkers.

Notably, a direct comparison between pre- and post-treatment patients revealed a near-significant difference in the frequency of both CD56 dim ( p = 0.0508) and CD56 bright NK cell subsets ( p = 0.0809) ( Figure 5B ).

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An analysis for the CD56 dim NK cell population was performed; patients with a high percentage showed a trend toward lower survival probability (log-rank HR = 2.436), but the difference was not statistically significant (log-rank p = 0.1831; 95% CI: 0.6553-9.055) (not shown).

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In the pre-treatment group, there was a trend toward an expansion of the CD56 dim NK cell subset, although this increase did not reach statistical significance (HD vs.

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