Clinical Evaluation of Oxidative Stress Biomarkers in Cirrhosis: Associations with Child-Pugh Class and Hepatic Encephalopathy.

Diagnostics (Basel) · 2025 · PMC12650868 · PMID 41300878

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0900

boldest claim

The sentences

highly significantp < 0.001actually significant

In contrast, classical liver function markers showed highly significant differences: albumin was markedly reduced in class C (2.50 [2.40–2.70] g/dL vs. 3.20 [2.80–3.40] g/dL, p < 0.001), while INR was significantly increased (1.70 [1.50–1.80] vs. 1.30 [1.20–1.40], p < 0.001).

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did not reach statistical significancep = 0.085so close (0.05 < p ≤ 0.1)

59 years), but the difference did not reach statistical significance ( p = 0.085).

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a negative trendp = 0.09so close (0.05 < p ≤ 0.1)

near-significantp = 0.09so close (0.05 < p ≤ 0.1)

The only near-significant association was a negative trend between 8-iso-PGF2α and total bilirubin (ρ = −0.18, p = 0.09).

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