Sarcopenia and Muscle Dysfunction in Osteogenesis Imperfecta: Insights from A Pilot Study.

J Musculoskelet Neuronal Interact · 2025 · PMC12684263 · PMID 41324214

Europe PMC

hedged sentences

0.0720

closest p · 1.4× alpha

0.5680

boldest claim

The sentences

did not reach statistical significancep = 0.072so close (0.05 < p ≤ 0.1)

As presented in Table 2 , right-leg ultrasound measurements revealed lower mean skin thickness, gastrocnemius thickness, and pennation angle in individuals with OI compared to healthy controls, although these differences did not reach statistical significance (p = 0.072, p = 0.259, and p = 0.350, respectively).

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showed a trendp = 0.568not close (p > 0.1)

OI patients showed a trend towards higher mean right-leg fat thickness than the control group (0.56±0.33 cm vs. 0.50±0.18 cm, p = 0.568).

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a negative trendno p-value reported

As presented in Table 5 , the relationship between handgrip strength and functional parameters showed a negative trend, though statistical significance was not reached.

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