Although a downward trend was observed, the reduction did not reach statistical significance ( p = 0.07) ( Figure 2 ).
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Pentraxin 3 Levels Reflect Inflammatory and Parasitic Activity in Human Visceral Leishmaniasis.
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Because most post-treatment samples in our current study were collected early after therapy completion, this timing likely explains why the paired PTX3 reduction failed to reach statistical significance ( p = 0.07) despite a downward trend.
Conclusions PTX3 concentrations were markedly elevated during active visceral leishmaniasis and showed a trend toward decline after treatment.