Aggressive Juvenile-Onset Respiratory Papillomatosis in a High HIV Prevalence Setting: Clinical Predictors of Severity in South Africa.

Open Forum Infect Dis · 2026 · PMC12750325 · PMID 41477532

Europe PMC DOI

hedged sentences

0.3800

closest p · 7.6× alpha

0.5900

boldest claim

The sentences

showed a trendP = .38not close (p > 0.1)

Similarly, viral load levels at baseline did not significantly differ between groups, although patients with HIV viral loads <1000 showed a trend toward lower odds of having AD compared with those with viral loads >1000 (adjusted OR:0.58; 95%CI: 0.17–2.00; P = .38).

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did not reach statistical significanceP = .59not close (p > 0.1)

Regarding immunological parameters, children with a CD4 + count <200 were less likely to have AD compared with those with CD4 + counts >500, although the results did not reach statistical significance (adjusted OR:0.51; 95%CI: 0.05–5.82; P = .59).

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a clear trendno p-value reported

Patient HIV status revealed a clear trend toward an increased likelihood of AD, with PWHIV showing higher odds of the disease.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.