Barely Significant
← all excerpts

The placental effects of trisomy for human chromosome 21 orthologs in four mouse models of Down syndrome.

Biol Open · 2025 · PMC12755066 · PMID 41342252

Europe PMCDOI
3
hedged sentences
0.0525
closest p · 1.0× alpha
0.0525
boldest claim

The sentences

approached significanceP =0.0525so close (0.05 < p ≤ 0.1)
Quantification showed increased APP expression in the trisomic labyrinth that approached significance ( P =0.0525) but no difference in APP expression in the trisomic JZ ( Fig. 5B ).

also in 8,237 other papers

did not reach statistical significanceno p-value reported
Ifnar1 expression in Ts66Yah measured by qPCR showed a corresponding trend towards higher levels of expression in Ts66Yah mild placentas, but these differences did not reach statistical significance (data not shown).

also in 111,027 other papers

showed a trendno p-value reported
The results showed a trend towards lower expression of full-length Sod1 in trisomic Ts1Cje placentas ( Fig. 1D ; Fig.

also in 53,322 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.