Barely Significant
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Real-World Outcomes of Immediate Femoral Sheath Removal After Emergency Embolization in the Age of Ultrasound-Guided Device-Assisted Vascular Closure.

Diagnostics (Basel) · 2025 · PMC12785840 · PMID 41515534

3
hedged sentences
0.0890
closest p · 1.8× alpha
0.0890
boldest claim

The sentences

showed a trendp = 0.089so close (0.05 < p ≤ 0.1)
While pre-procedural INR > 1.5 showed a trend towards increased risk (OR 2.78), it did not reach statistical significance in this model ( p = 0.089).

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Age ( p = 0.246), gender ( p = 0.489), BMI ( p = 0.555), obesity ( p = 0.481), smoking history ( p = 0.584), history of DM ( p = 0.606), history of HTN ( p = 0.796), history of CAD ( p = 0.092), history of PVD ( p = 0.573), sheath size ( p = 0.789), type of VCD ( p = 0.106), pre-procedural antithrombotic therapy ( p = 0.442), pre-procedural hemoglobin ≤100 g/L ( p = 0.779), and pre-procedural estimated glomerular filtration rate < 60 mL/min/1.73 m 2 ( p = 0.260) did not reach statistical significance.

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a strong trendno p-value reported
Elevated INR > 1.5 (OR 3.55, 95% CI: 0.84–14.92, p = 0.084) and antithrombotic use (OR 2.74, 95% CI: 0.79–9.49, p = 0.112) were not found to be significant but displayed a strong trend towards re-intervention.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.