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Male Stress Is Associated with Ovarian and Endometrial Responses in ICSI Cycles: Is Seminal Plasma the Linchpin?

Int J Mol Sci · 2026 · PMC12786501 · PMID 41516408

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No significant differences were found in EMT and the number of fertilized oocytes, while differences in the number of collected and mature oocytes were near statistical significance ( Table 1 ). 2.2.

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near-significantno p-value reported
A strong positive correlation was observed between seminal NA levels and the FSH/LH ratio, with seminal NA also showing a near-significant correlation with LH.

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showed a trendno p-value reported
Salivary CORT was negatively correlated with male age and showed a trend toward statistical significance with female age and duration of infertility.

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Additionally, seminal NA showed a negative correlation with EMT, which was very close to statistical significance, a strong negative correlation with the total number of collected and mature oocytes, and a weak but significant correlation with fertilized oocytes.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.