Barely Significant
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Pulsed Radiofrequency Analgesia Alters EEG Spatiotemporal Dynamics: A Microstate-Based Exploratory Study.

Pain Ther · 2026 · PMC12804541 · PMID 41184600

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The sentences

a strong trendp = 0.016actually significant
These analyses, which should be interpreted with caution in the absence of an overall significant effect, suggested a specific pattern: Delta TM D to E was reduced in the pre-PRF group compared to the HC group, with a strong trend ( p = 0.016, uncorrected for multiple comparisons; Fig. 5 a, Table 4 ).

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Although the duration, occurrence, or coverage of microstate E did not reach statistical significance, all three metrics were consistently lower in the pre-PRF group than in both the HC and post-PRF group.

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showed a trendno p-value reported
Notably, this reduction showed a trend toward normalization after treatment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.