Barely Significant
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Reduced triacylglycerols and lipid droplets are associated with resilience to Alzheimer's disease.

Alzheimers Dement · 2026 · PMC12865325 · PMID 41630598

Europe PMCDOI
3
hedged sentences
0.0023
closest p · 0.0× alpha
0.0023
boldest claim

The sentences

a negative trendp = 0.0023actually significant
Western blot analysis confirmed that ABHD6 protein levels were consistent across all samples, whereas gel‐based ABPP analysis revealed that ABHD6 activity was significantly lower in resilient individuals, with a negative trend in AD donors (Figure 4G‐I , Figure S4 : resilient vs control, p = 0.0023; AD vs control, p = 0.068, AD vs resilient, p = 0.089).

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showed a trendno p-value reported
ABHD6 was significantly reduced in resilient donors and showed a trend toward lower levels in AD.

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did not reach statistical significanceno p-value reported
In resilient individuals, oxylipins trended to increase, but this did not reach statistical significance (Figure 2B, D ).

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