Barely Significant
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One-Year Efficacy and Tolerance of Myofix Defocus Spectacles for Control of Myopia Progression.

Ophthalmol Ther · 2026 · PMC12882891 · PMID 41222872

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did not reach statistical significancep = 0.214not close (p > 0.1)
showed a trendno p-value reported
Children who used inverted contrast settings on electronic devices showed a trend for lower SE progression compared to those using standard contrast settings, although this difference did not reach statistical significance (Student’s t test, p = 0.214; – 0.11 D vs. – 0.23 D, respectively, see Supplementary Fig. 1).

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a clear trendno p-value reported
In the control group (left panel), most children showed a clear trend toward increasing myopia over the 12-month follow-up, with relatively consistent rates of progression across individuals.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.