Pre-transplant physical performance, muscle quality, and body composition as predictors of post-liver transplant outcomes: a retrospective cohort study.

In our cohort, those in the highest tertile (> 47.69 cm 2 /m 2 ) had lower mortality compared to those in the lowest tertile (< 37.95 cm 2 /m 2 ), with a significant trend across tertiles ( p = 0.049), supporting the potential prognostic relevance of L3SMI.

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A higher L3 muscle area (> 29.83 cm 2 ) was associated with a reduced risk of post-transplant mortality in Model 1 (HR: 0.35; 95% CI 0.12, 0.98), Model 2 (HR: 0.29; 95% CI 0.09, 0.92), and Model 3 (HR: 0.28; 95% CI 0.08, 0.99); however, the overall trend did not reach statistical significance in Model 3 ( p -trend = 0.066).

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This aligns with our findings, which showed a trend toward reduced mortality among patients with higher L3SMI values.

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