Tumor-Associated Neutrophils and Desmoplastic Reaction in Breast Cancer Microenvironment: Association with Tumor Grade and Clinicopathological Features.

Cancers (Basel) · 2026 · PMC12897329 · PMID 41681878

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0590

boldest claim

The sentences

near-significantp = 0.051so close (0.05 < p ≤ 0.1)

A near-significant relationship was identified between DR type and tumor differentiation grade (χ 2 = 9.448, p = 0.051), with mature stroma most common in Grade 1 tumors, keloid-like stroma in Grade 2, and myxoid stroma in Grade 3.

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a clear trendp = 0.059so close (0.05 < p ≤ 0.1)

did not reach statistical significanceno p-value reported

Although post hoc comparisons did not reach statistical significance after Bonferroni correction, a clear trend toward higher TAN counts was observed in the c-erbB2-positive group compared with the c-erbB2-negative group (mean rank = 36.65 vs. 28.91, p = 0.059) ( Table 4 , Chart 4 ).

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approaches statistical significanceno p-value reported

Our study also found an association that approaches statistical significance between the type of DR and the tumor grade.

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