Ultrastructural and Immunohistochemical Alterations in Muscle and Vascular Tissues in Patients with Omphalocele.

Int J Mol Sci · 2026 · PMC12898674 · PMID 41683881

Europe PMC DOI

hedged sentences

0.0518

closest p · 1.0× alpha

0.0520

boldest claim

The sentences

a strong trendp = 0.0518so close (0.05 < p ≤ 0.1)

Paired comparison using the Wilcoxon signed-rank test (non-parametric) showed a strong trend toward higher CD34 expression in the subumbilical region, reaching the limit of statistical significance (U = 5.0, p = 0.0518).

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a strong trend toward significancep = 0.052so close (0.05 < p ≤ 0.1)

In contrast, CD34 displayed higher sub-umbilical scores (median 3) compared with supraumbilical (median 2), with a strong trend toward significance ( p = 0.052) and a large effect size, suggesting increased microvascular density/activation in the sub-umbilical segment.

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did not reach statistical significanceno p-value reported

These findings suggest a trend toward increased DUX4 expression in the subumbilical region, although this did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.