Effectiveness of supervised vs brief counselling physical activity promotion interventions in breast cancer survivors on aromatase inhibitors: the PAC-WOMAN randomized controlled trial.

Almost significant improvements were observed in the ExG in upper limb flexibility, namely in the one with worst scores at start (MD [95% CI]: ExG – 3.6 cm [0.9; 6.4], p = 0.009).

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Future perspectives were significantly different between PAC and CG post-intervention (MD [95% CI]: 23.7 [6.2; 41.3], p = 0.004, scale range 0–100) and borderline significant between ExG and CG (MD [95% CI]: 21.8 [4.2; 39.3], p = 0.009, scale range 0–100).

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The increase in total PA observed in PAC approached significance (MD [95% CI]: 179 min/week [41; 316], p = 0.011).

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ExG improved global health status, physical functioning and physiological indicators (e.g., fitness, body composition) over time; PAC enhanced future perspectives, body image functioning, breast symptoms, and other psychological outcomes, with changes in depressive symptoms (-1.4 [-2.4; -0.3]) and life satisfaction (0.8 [0.2; 1.5]) approaching significance.

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Objectively measured PA showed no significant effects in either intervention group, except for a near-significant MVPA increase of 107 min/week [95% CI: 4; 209] over time in ExG.

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