Ozone Treatment Attenuates Neuroinflammation and Alters miRNA Expression in a Rat Model of Post-Traumatic Epilepsy.

Neurochem Res · 2026 · PMC12923413 · PMID 41718951

Europe PMC DOI

hedged sentences

0.0510

closest p · 1.0× alpha

0.0670

boldest claim

The sentences

a near-significant trendp = 0.051so close (0.05 < p ≤ 0.1)

While apoptosis showed a near-significant trend (p = 0.051), no significant differences were detected for cortical congestion, inflammation, or hemorrhage (p > 0.05).

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a decreasing trendp = 0.067so close (0.05 < p ≤ 0.1)

Although seizure severity, latency, and duration were not significantly altered, seizure frequency showed a decreasing trend ( p = 0.067).

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showed a trendp = 0.067so close (0.05 < p ≤ 0.1)

Seizure frequency showed a trend toward reduction following ozone treatment (1.20 ± 0.20 vs. 0.70 ± 0.15; p = 0.067).

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did not reach statistical significanceno p-value reported

Although miRNA expression levels did not reach statistical significance, their directional consistency with biochemical and histological findings is noteworthy.

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