Circulating Inflammatory and Mitochondrial Biomarkers Associated with Cachexia in Advanced Non-Small Cell Lung Cancer.

Cancers (Basel) · 2026 · PMC12939877 · PMID 41749907

Europe PMC DOI

hedged sentences

0.0597

closest p · 1.2× alpha

0.1300

boldest claim

The sentences

near-significantp = 0.0597so close (0.05 < p ≤ 0.1)

Several biomarkers demonstrated near-significant trends including IL-5 (OR 0.57, 95% CI: 0.22–1.02, p = 0.0597) and MDC (OR 0.49, 0.08–1.26, p = 0.144) but did not reach statistical significance. 4.

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showed a trendp = 0.083so close (0.05 < p ≤ 0.1)

Additionally, sVCAM-1 showed a trend towards reduced cachexia risk ( p = 0.083).

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did not reach statistical significancep = 0.13not close (p > 0.1)

27.0 ± 7.0), though this difference did not reach statistical significance ( p = 0.13).

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