Predicting the Unpredictable: Prognostic Role of Systemic Inflammatory Indices and Tumor Biology of Neoadjuvant Chemotherapy Response in Gastric and Gastroesophageal Junction Cancer-Insights from a Systematic Review and Real-World Experience.

J Clin Med · 2026 · PMC12941500 · PMID 41753172

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did not reach statistical significanceno p-value reported

18.9 months), this difference did not reach statistical significance.

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a clear trendno p-value reported

Although our study did not identify a statistically significant survival difference between patients receiving FLOT and those receiving non-FLOT regimens ( p > 0.05), the Kaplan–Meier curves ( Figure 2 ) demonstrate a clear trend toward improved outcomes with FLOT.

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showed a trendno p-value reported

Results: Although FLOT showed a trend toward improved overall survival (OS) (median not reached vs. 18.9 months), this difference did not reach statistical significance.

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