Subretinal injection of balanced salt solution for macular edema secondary to retinal vein occlusion.

The surgery group also showed a strong trend toward a lower recurrence rate (40.0% vs. 88.9%, p = 0.051) and a longer median time to recurrence (10.0 vs. 4.0 months), though the latter was not statistically significant (log-rank p = 0.503).

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In terms of recurrence, surgical treatment showed a favorable trend inin recurrence rate and a clinically meaningful extension of the time to recurrence.

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Notably, our structure-function correlation analysis confirmed a dissociation in this refractory cohort, showing a negative trend between the magnitude of edema reduction (ΔCMT) and visual gain (ΔBCVA).

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While a trend in visual improvement was observed, the observed visual acuity improvement did not reach statistical significance over anti-VEGF therapy after adjustment.

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