Educational attainment is associated with reduced functional decline in Puerto Ricans with elevated pTau181.

CDR-FUNC by APOE ε4 carrier status in high and low EA groups Among those with high pTau181, APOE ε4 carrier status showed a trend towards worse functional performance differences in the low EA subgroup, where ε4 carriers had greater CDR-FUNC scores than non-carriers (Median ε4 non−carrier = 2, Median ε4 carrier = 8; p = 0.06).

also in 37,073 other papers

However, this trend did not reach statistical significance.

also in 77,393 other papers

No significant education × APOE ε4 interaction was observed, though a negative trend suggested that increasing education attenuated ε4-related impairment.

also in 2,747 other papers