Efficacy and Safety of Tranexamic Acid in Sleeve Gastrectomy: A Double-Blind Randomized Controlled Trial.

Although a trend toward lower transfusion requirements was noted with TXA, this did not reach statistical significance, likely owing to the low overall frequency of transfusions in MBS [ 7 ].

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Regression analysis confirmed that TXA administration had no independent association with platelet count, whereas the association with lower WBC approached significance but did not remain robust after adjustment (Table 4 ).

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This near-significant signal suggests that TXA’s hematological benefit may be more evident in larger cohorts or in patients at higher bleeding risk.

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