Prebiotics attenuate depressive-like behavior, neuroinflammation and synaptic plasticity in Parkinson's disease by modulating butyrate-producing gut bacteria.

In relation to the Lactobacillaceae family, one-way ANOVA did not reach statistical significance (F (3, 8) = 2.878, p = 0.1031).

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In the PD group showed a trend to increase the relative abundance compared to the other group (Fig. 6 B).

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The first data we can extract from the sequencing and identification of bacteria are related to bacterial communities’ α and beta diversity; there was a clear trend towards a decrease in diversity in the group subjected to PD and an increase in the treated groups, although without significance (Fig. 4 ).

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