Vitamin D status and site-specific fracture pattern associations in older adults with fragility fractures: a cross-sectional analysis of 2543 patients.

A clear trend was observed across age groups, with serum 25(OH)D concentrations decreasing with increasing age; this decline was statistically significant between groups with larger age spans ( Supplementary Table S1 ).

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Coronary artery disease showed a trend toward association but was not statistically significant ( p = 0.075). 3.4.

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Our study also found that coronary heart disease was associated with vitamin D deficiency in univariate analysis ( p = 0.075), though this association did not reach statistical significance after multivariable adjustment; in contrast, a meta-analysis by Wang et al. reported a significant association between low vitamin D status and elevated cardiovascular disease (CVD) risk ( 28 ).

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