Determinants and long-term outcomes of treatment delays in young and middle-aged acute ischemic stroke patients: a prospective cohort study.

BMC Neurol · 2026 · PMC13154868 · PMID 41913141

Europe PMC DOI

hedged sentences

0.0820

closest p · 1.6× alpha

0.0880

boldest claim

The sentences

did not reach statistical significanceP = 0.082so close (0.05 < p ≤ 0.1)

While the associations did not reach statistical significance, binary logistic regression indicated a strengthening negative effect on prognosis over time ( OR decreased from 0.50 at 1 month to 0.28 at 6 months; P = 0.082 and P = 0.084, respectively).

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a negative trendP = 0.088so close (0.05 < p ≤ 0.1)

approaching significanceP = 0.088so close (0.05 < p ≤ 0.1)

Similarly, multiple linear regression showed a negative trend between longer treatment delays and lower quality of life scores at both time points, with the effect approaching significance at 6 months ( P = 0.088).(Tables 7 and 8 ).

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