Cardiac Dose and Survival Outcomes Following Stereotactic Body Radiation Therapy for Primary and Metastatic Lung Tumors: A Substructure-Based Analysis.

Adv Radiat Oncol · 2026 · PMC13202019 · PMID 42206292

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

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boldest claim

The sentences

a strong trendP = .05actually significant

A higher mean dose to the heart base showed a strong trend toward reduced survival (HR, 3.70; P = .05).

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showed a trendP = .05actually significant

In the present study, we observed that higher EQD2 mean dose to base of the heart showed a trend toward reduced OS (HR, 3.7; P = .05).

also in 45,030 other papers

a clear trendno p-value reported

Moreover, a clear trend toward reduced survival with higher doses to the base of the heart underscores the importance of this region as a potential target for future dose-sparing strategies. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.