Barely Significant
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Molecular Classification as a Predictor of Nodal Involvement and Survival Outcomes in Presumed Early-Stage Endometrial Cancer.

Cancers (Basel) · 2026 · PMC13204788 · PMID 42192987

3
hedged sentences
0.0560
closest p · 1.1× alpha
0.0560
boldest claim

The sentences

a strong trendp = 0.056so close (0.05 < p ≤ 0.1)
In the MMRd subgroup, LVSI showed a strong trend toward increased recurrence risk (OR 5.17, 95% CI 0.96–27.91, p = 0.056).

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showed a trendno p-value reported
In the multivariate analysis, no variable retained independent statistical significance, although molecular classification and prognostic risk group showed a trend toward association with recurrence ( Table 4 ).

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This is particularly relevant for the POLE-mutated subgroup and for stratified and multivariable analyses, where wide confidence intervals were observed, and some associations did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.