Barely Significant
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Discovery of novel biomarkers associated with myocardial fibrosis in chimpanzees (<i>Pan troglodytes</i>).

Front Vet Sci · 2026 · PMC13225971 · PMID 42238790

Europe PMCDOI
3
hedged sentences
0.0570
closest p · 1.1× alpha
0.0650
boldest claim

The sentences

approached significancep = 0.057so close (0.05 < p ≤ 0.1)
When considering only the ELISA data from the initial subset of 10 chimpanzees (the same individuals as in Study A) in isolation, no statistically significant differences were found for any of the three proteins, though ICAM-2 approached significance: ICAM-2 (Mann–Whitney test p = 0.057), AXL (Welch’s t test p = 0.341) and PECAM-1 (Welch’s t test p = 0.387). 3.3.

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a strong trendp = 0.065so close (0.05 < p ≤ 0.1)
Additionally, a targeted sub-analysis of only those animals sampled at the time of death (time to death 0 months; N = 13) maintained a strong trend toward elevation in the diseased group (Welch’s t (8.36) = 1.68, p = 0.065).

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