highly significantp = 0.006
Oropharyngeal Secretion Accumulation Scale (Murray Score) Change: The most pronounced heterogeneity was observed in Murray score changes, with highly significant interaction test ( p = 0.006).
Oropharyngeal Secretion Accumulation Scale (Murray Score) Change: The most pronounced heterogeneity was observed in Murray score changes, with highly significant interaction test ( p = 0.006).
SSA Improvement: The improvement magnitude of SSA across strata ranged from −1.27 to 4.67 points overall, with the second stratum approaching significance ( β = 4.67 [95% CI: −0.11-9.44], p = 0.056).
The interaction test revealed borderline significant heterogeneity ( p = 0.116), suggesting possible treatment effect variation by propensity score stratification.
Although unadjusted analysis (HR = 1.645 [0.817–3.314], p = 0.163), multivariable-adjusted analysis (HR = 1.000 [0.039–25.381], p = 0.999), PS-adjusted analysis (HR = 1.892 [0.870–4.115], p = 0.108), and PSM analysis (HR = 1.811 [0.640–5.124], p = 0.263) did not reach statistical significance, the consistency in direction of effect estimates across these methods supported the credibility of the primary finding.
The Log-rank test did not reach statistical significance ( p = 0.095), indicating that the difference in nasogastric tube removal time between groups was borderline non-significant in unadjusted analysis.